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    Home » Wellness & Lifestyle » Devi Sridhar: Scientists say when we eat affects health
    Wellness & Lifestyle

    Devi Sridhar: Scientists say when we eat affects health

    Oliver MarshBy Oliver Marsh5 May 2026
    Researcher reviewing data from a meta-analysis on meal timing and metabolic health

    Eating earlier in the evening can significantly improve key health markers – and the benefits appear to go beyond simply cutting calories, according to a major new meta-analysis. The findings challenge the long-standing “calories in, calories out” narrative that has dominated weight-loss and dietary advice for decades.

    What the study found

    Researchers analysed 41 randomised controlled trials involving around 2,200 participants – 42 per cent of whom were women – with a mean age range of 19 to 69 years. The studies tracked participants for between four and 48 weeks and examined the impact of different meal-timing patterns. Early time-restricted eating was defined as finishing the last meal before 5pm; mid-time as a final meal between 5pm and 7pm; and late-time as eating after 7pm.

    The results showed that eating earlier in the evening – whether finishing before 5pm or before 7pm – was associated with significant improvements in body weight, body mass index, body fat percentage, waist circumference, blood pressure and a range of metabolic markers, including levels of glucose, insulin and triglycerides in the blood.

    Crucially, several of the trials demonstrated that these benefits occurred even when participants did not reduce their overall calorie intake. The positive effects on fasting blood glucose, fasting insulin and triglycerides were independent of how much people ate overall. In other words, the timing of meals appeared to have its own independent effect on metabolic health.

    The science behind meal timing

    The researchers behind the meta-analysis point to the body’s internal circadian rhythms as the likely explanation. Our metabolism does not operate at a constant rate throughout the day; it fluctuates according to a 24-hour clock influenced by light-dark cycles and feeding-fasting patterns. One of the most important aspects of this rhythm is insulin sensitivity – the body’s ability to manage sugar. Studies have shown that insulin sensitivity is higher earlier in the day and lower at night. The body releases the most insulin, the hormone that helps move sugar from the blood into cells, between midday and 6pm, with the lowest release during sleep.

    This means that the same meal eaten in the evening will cause a higher blood sugar spike than if it were eaten in the morning. Because of how hormones are secreted, we are better equipped to handle food intake in the morning and afternoon compared with the evening and night. Eating earlier aligns food intake with the body’s natural peaks in insulin secretion and glucose disposal, allowing metabolism to work more efficiently. This area of research is known as chrononutrition – the study of how the timing of food intake interacts with the body’s internal clocks to influence health.

    The findings also help explain why early time-restricted eating (eTRE) – confining meals to a window earlier in the day – has been shown to reduce elevated blood sugar levels and improve insulin resistance, even without calorie restriction. While weight loss itself is a known factor in metabolic health, this study suggests that the temporal pattern of eating offers additional, independent benefits.

    Practical implications – and the risks of going too far

    The research offers a nuanced alternative to traditional dietary advice, which has long focused on what to eat and how much to eat. Government dietary pyramids, calorie counts on packaging and standard nutritional guidance have all emphasised reducing calories, eating more vegetables and limiting soft drinks and junk foods. That advice remains valid, but it can be difficult to sustain over months and years. Constant calorie counting and the classification of foods as “good” or “bad” can not only be time-consuming and boring – it can tip into disordered eating. Orthorexia nervosa, described by the British Dietetic Association as a “pathological fixation on healthy eating”, is a recognised form of disordered eating that can lead to social isolation, anxiety and even malnutrition, despite the individual’s focus on food quality rather than quantity.

    For those who want to apply the new findings, the practical challenges are considerable. Finishing dinner before 5pm – or even before 7pm – clashes with the structure of modern life. Late shift work, social commitments and the desire to eat with family or friends make early evening meals difficult for many people. Shift workers, who make up around 18 per cent of UK employees, face particular difficulties because their altered eating patterns, including late-night meals, are linked to adverse metabolic outcomes and increased risk of obesity, cardiovascular disease and type 2 diabetes. At the same time, a recent cultural shift towards “early dining” has been observed in the UK, with a rise in earlier restaurant bookings, possibly driven by wellness trends and hybrid working.

    Professor Devi Sridhar, chair of global public health at the University of Edinburgh and author of How Not to Die (Too Soon), has written about the importance of societal accountability for health outcomes rather than placing all responsibility on individuals. Sridhar, who is also a certified Level 3 personal trainer, argues that the new evidence should make life easier, not harder. If you are going to eat a piece of chocolate cake – or a croissant – it is better to have it earlier in the day, when your body is better primed to handle it. “I’m not saying have chocolate for breakfast,” she writes, “but I am saying that if you’re going to eat chocolate tomorrow, maybe have it before 5pm.”

    Anxiety Blood Pressure Diabetes Obesity Public Health Sleep Weight Loss
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    Oliver Marsh
    Oliver Marsh

    Mental Health & Lifestyle Correspondent
    Oliver Marsh reports on mental health and wellness for Health News Daily. He covers NHS mental health services, workplace wellbeing, children's mental health, anxiety, depression and modern approaches to healthy living. A certified Mental Health First Aider, Oliver is passionate about breaking the stigma around mental health and making evidence-based wellbeing advice accessible to all. His reporting bridges the gap between clinical mental health news and practical lifestyle guidance for UK readers.
    · Certified Mental Health First Aider (MHFA England), peer support volunteer, lived experience of NHS Talking Therapies pathway
    · ADHD and autism in adults, anxiety and depression, CAMHS and children's mental health, workplace burnout, sleep science, nutrition and ultra-processed foods, NHS mental health service access

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